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KMID : 0861420110150020060
Korean Journal of Nuclear Medicine Technology
2011 Volume.15 No. 2 p.60 ~ p.64
Usefulness of Image Registration in Brain Perfusion SPECT
Song Ho-Jun

Lim Jung-Jin
Kim Jin-Eui
Kim Hyun-Joo
Abstract
Purpose:The brain perfusion SPECT is the examination which is able to know adversity information related
brain disorder. But brain perfusion SPECT has also high failure rates by patient¡¯s motions. In this case, we have
to use two days method and patients put up with many disadvantages. We think that we don¡¯t use two days
method in brain perfusion SPECT, if we can use registration method. So this study has led to look over
registration method applications in brain perfusion SPECT.

Materials and Methods:Jaszczak, Hoffman and cylindrical phantoms were used for acquiring SPECT image data on varying degree in x, y, z axes. The phantoms were filled with 99mTc solution that consisted of a radioactive concentration of 111 MBq/mL. Phantom images were acquired through scanning for 5 sec long per frame by using Triad XLT9 triple head gamma camera (TRIONIX, USA). We painted the ROI of registration image in brain data. So we calculated the ROIratio which was different original image counts and registration image counts.

Results:When carring out the experiments
under the same condition, total counts differential was from 3.5% to 5.7% (mean counts was from 3.4% to 6.8%)
in phantom and patients data. In addition, we also run the experiments in the double activity condition. Total
counts differential was from 2.6% to 4.9% (mean counts was from 4.1% to 4.9%) in phantom and patients data.

Conclusion:We can know that original and registration data are little different in image analysis. If we use the
image registration method, we can improve disadvantage of two days method in brain perfusion SPECT. But we
must consider image registration about the distance differences in x, y, z axes
KEYWORD
Brain perfusion SPECT, Image registration, Two days method
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